Three-Dimensional Electron Microscopy of Human Umbilical Cord Tissue Allograft Pre and Post Processing: A Literature Comparison

One in four adults the US suffer from cartilage degeneration of Intervertebral Disc (DDD) or load bearing joints (DJD). Since is avascular, it has a limited regenerative capacity. Conventional non-surgical treatments provide brief symptomatic relief, have sided effects, and do not address defect itself. As such, new alternatives are needed. Perinatal birth tissue allografts novel frontier for bio-mechanical engineering research. The tissues interest include umbilical cord-derived Wharton’s Jelly (WJ). This study assessed WJ samples via ZEISS Supra 55VP FieldEmission Scanning Electron Microscope (SEM) at 100 300 nm resolution scales. captured images pre post-processed structural matrices were analyzed against themselves peer-reviewed SEM articular cartilage, intervertebral disc muscle fascia. found to be comparable human fascia on qualitative quantitative level. first that we aware of, demonstrate collagen analogous structure joints, discs,